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ニュース

2023年04月06日
大学院生の杉本君、増田准教授の論文がNucleic Acids Researchに掲載されました
2022年07月29日
金尾助教の論文がLife Sci Allianceに掲載されました
2019年11月18日
増田准教授のReviewがCrit Rev Biochem Mol Biolに掲載されました
2019年10月20日
増田准教授の論文がの論文がJBC editors’ picksに選ばれました
2019年10月11日
増田准教授の論文がJBCに掲載されました
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主要論文　（2010～）

  • Sugimoto Y, *Masuda Y, Iwai S, Miyake Y, Kanao R, Masutani C. Novel mechanisms for the removal of strong replication-blockingHMCES- and thiazolidine-DNA adducts in humans. Nucleic Acids Research, doi:10.1093/nar/gkad246

    Kanao R, Kawai H, Taniguchi T, Takata M, and *Masutani C. RFWD3 and translesion DNA polymerases contribute to PCNA modification–dependent DNA damage tolerance. Life Sci Alliance, 5, e202201584. doi: 10.26508/lsa.202201584. PMID: 35905994

    *Masuda Y., Mitsuyuki S., Kanao R., Hishiki A., Hashimoto H., Masutani C. (2018) Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway. Nucleic Acids Res. doi.org/10.1093/nar/gky943

    Kashiwaba S., Kanao R., Masuda Y., Matsuo-Kusumoto R., Hanaoka F., *Masutani C. (2015) USP7 Is a Suppressor of PCNA Ubiquitination and Oxidative-Stress-Induced Mutagenesis in Human Cells. Cell Rep. 13, 2072-2080. doi:10.1016/j.celrep.2015.11.014. PMID:26673319

    Masuda Y., Kanao R., Kaji K., Ohmori H., Hanaoka F., *Masutani C. (2015) Different types of interaction between PCNA and PIP boxes contribute to distinct cellular functions of Y-family DNA polymerases. Nucleic Acids Res. 43, 7898-7910. doi: 10.1093/nar/gkv712. PMID:26170230

    Kanao R., Masuda Y., Deguchi S., Yumoto-Sugimoto M., Hanaoka F., *Masutani C. (2015) Relevance of Simultaneous Mono-Ubiquitinations of Multiple Units of PCNA Homo-Trimers in DNA Damage Tolerance. PLoS One 10, e0118775. doi: 10.1371/journal.pone.0118775. PMID: 25692884

    *Masuda Y., Suzuki M., Kawai H., Hishiki A., Hashimoto H., Masutani C., Hishida T., Suzuki F., *Kamiya K. (2012) En bloc transfer of poly-ubiquitin chains to PCNA in vitro is mediated by two human E2-E3 pairs. Nucleic Acids Res. 40, 10394-10407. PMID: 22904075

    Biertümpfel C., Zhao Y., Kondo Y., Ramón-Maiques S., Gregory M., Lee J.Y., Masutani C., Lehmann A. R., *Hanaoka F., *Yang W. (2010) Structure and mechanism of human DNA polymerase η. Nature 465, 1044-1048. PMID: 20577208

主要論文（2010以前）

  • Masutani C., Kusumoto R., Yamada A., Dohmae N., Yokoi M., Yuasa M., Araki M., Iwai S., Takio K., *Hanaoka F. (1999) The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η. Nature 399, 700-704. PMID: 10385124 (Citation: 1014)
  • Masutani C., Kusumoto R., Iwai S., *Hanaoka F. (2000) Mechanisms of accurate translesion synthesis by human DNA polymerase η. EMBO J. 19, 3100-3109. PMID: 10856253 (Citation: 381)
  • Masutani C., Araki M., Yamada A., Kusumoto R., Nogimori T., Maekawa T., Iwai S., *Hanaoka F. (1999) Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO J. 18, 3491-3501. PMID: 10369688 (Citation: 346)
  • Masutani C., Sugasawa K., Yanagisawa J., Sonoyama T., Ui M., Enomoto T., Takio K., Tanaka K., van der Spek P.J., Bootsma D., Hoeijmakers J.H.J., *Hanaoka F. (1994) Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homolog of yeast RAD23. EMBO J. 13, 1831-1843. PMID: 8168482 (Citation: 312)
  • Matsuda T., Bebenek K., Masutani C., Hanaoka F., *Kunkel T.A. (2000) Low fidelity DNA synthesis by human DNA polymerase η. Nature 404, 1011-1013. PMID: 10801132 (Citation: 299)
  • McCulloch S.D., Kokoska R.J., Masutani C., Iwai S., Hanaoka F., Kunkel T.A. (2004) Preferential cis-syn thymine dimer bypass by DNA polymerase η occurs with biased fidelity. Nature 428, 97-100. PMID: 14999287 (Citation: 195)